About Aspen Oss

Aspen Oss supplies complex Active Pharmaceutical Ingredients (APIs) of very high quality worldwide with an excellent customer service. Based on this value proposition our customers are able to build and maintain a sustainable position in the world of the pharmaceutical business. Our high level technology is developed over many years by our highly motivated and knowledgeable staff and business partners. Teamwork is and has been a key success factor in these developments. We act in a respectful manner towards society and environment. Safety, compliance and labour satisfaction are essential to support our business.

Working with us

Aspen Oss is a leading supplier of APIs.  Serving for many years a stable customer portfolio including global multinationals, generic manufacturers and innovative new tech start-ups, we understand what you need in an API partner.

We believe that the formation of closely aligned partnerships with our customers is the key to success in today’s business. We work from a deeply rooted and pro-active quality culture and are committed to delivering high quality APIs all the time, while developing and maintaining lasting partnerships with our customers. Our sales managers are partners with extensive product and practical business experience. Our Customer and Regulatory Support team has broad experience to support you at all stages from development through registration and commercialization.

When bringing your project to Aspen Oss, you will be sure to find a reliable quality partner, through our transparent and professional way of communication.

Producing complex APIs for almost 100 years

Aspen Oss has a proud history in the production of APIs, spanning over almost 100 years. The origins of Aspen Oss date back to 1923, when the owner of a slaughterhouse initiated the extraction of animal pancreases for the use in the production of insulin production. From these humble beginnings the operations have gradually been expanded, culminating in Aspen Oss’s position today as a global supplier and one of the world’s best known producers of steroid hormones APIs, many of which are registered and used in originator Drug Products. Aspen Oss is also well known for its production of Heparin Sodium, Chorionic Gonadotrophin and several peptides.

Production locations

Location Moleneind, Oss, The Netherlands

The Moleneind site, located in the heart of Oss, commenced operations back in 1923. Numerous activities are performed on site, including our peptide manufacturing, biochemical manufacturing and small scale chemical manufacturing.

Furthermore, our Process and Analytical Development, Quality Control and Quality Assurance departments are located at Moleneind, as well as our stability chambers.

> Inspection approvals: 

ANVISA, Dutch HA, KFDA, PMDA, Russian HA, Turkish HA, US FDA

Location Diosite, Oss, The Netherlands

The Diosite (“De Geer”) facility was constructed in the 1990’s and is a production facility dedicated to chemical manufacturing. This site contains a modern, computer-directed, multi-purpose factory used for larger production campaigns with reaction vessels up to a volume of 10,000 liters. Furthermore, the sieving, milling and micronisation of the APIs are performed at this site, in addition to the central warehousing and distribution operations.

>Inspection approvals: 

ANVISA, Dutch HA, KFDA, PMDA, Russian HA, Turkish HA, US FDA

Location Boxtel, The Netherlands

Since 1971 Aspen Oss runs a biochemical operation in Boxtel City (The Netherlands). In this dedicated facility, urine from pregnant women is collected in the Netherlands and further processed into the final API Chorionic Gonadotrophin (HCG). The facility has undergone a major renovation in 2018 including the building of a modern purification suite and the introduction of a virus filtration step, thereby meeting worldwide regulatory requirements.

> Inspection approvals: Dutch HA, PMDA, Russian HA, Turkish HA, US FDA

Location Sioux City, Iowa, USA

In our facility in Sioux City (Iowa, USA), in use since 1985, we collect porcine mucosa and produce a crude heparin, that is then transported to our facilities in Oss for final purification and product release. Having this Sioux City based facility in an important livestock area in the USA, provides close access to many large slaughterhouses, and thus to large mucosa quantities. Large-scale mucosa collection is indispensable to be able to continuously serve the world market needs for heparin sodium.

> Inspection approvals: US FDA

Good neighbourship

Aspen Oss would like to keep its neighbours, neighbouring companies and any other interested party informed about its activities on site. If you want to have more information, please click below on read more (available in Dutch language only).

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