Alkaloid products

Alkaloids are a group of naturally occurring chemical compounds that mostly contain a basic nitrogen atom although an alkaloid can have neutral and even weakly acidic properties. Alkaloids have pharmacological effects that can be used as medication. Examples are the local anesthetic and stimulant cocaine, the stimulant caffeine, nicotine, the analgesic morphine and the anti-malarial drug quinine.
Many synthetic and semi-synthetic drugs are structural modifications of the alkaloids, which were designed to enhance or change the primary effect of the drug and reduce unwanted side effects. For example, naloxone, an opioid receptor antagonist, is a derivative of thebaine which is present in opium.

Naloxone is a drug used to reduce the effects of opiate overdose, for example heroin or morphine overdose. The chemical structure of naloxone resembles that of oxymorphone, the only difference being the substitution of the N-methyl group with an allyl (prop-2-enyl) group. Naltrexone is an opioid receptor antagonist used primarily in the management of alcohol and opioid dependence rather than emergency overdose treatment. Naltrexone is the N-cyclopropylmethyl derivative of oxymorphone.
Alkaloid Active Ingredients produced by Aspen Oss are the following:
  • Naloxone hydrochloride
  • Naltrexone hydrochloride